Article -> Article Details

Here, CAS NO: 5390-04-5 refers to 4-Pentyn-1-ol, an important bifunctional organic compound used as a building block in synthetic chemistry. Its molecular formula is C₅H₈O and its molecular weight is approximately 84.12 g/mol. The molecule contains two particularly useful functional features—a primary alcohol group and a terminal alkyne—which provide opportunities for a range of chemical transformations.

What Is 4-Pentyn-1-ol?

4-Pentyn-1-ol, also known as pent-4-yn-1-ol, is a small unsaturated alcohol with a five-carbon chain. The hydroxyl group is positioned at one end of the molecule, while the terminal alkyne is located at the opposite end. This arrangement gives the compound useful synthetic flexibility because the two functional groups can participate in different chemical reactions.

4-Pentyn-1-ol has the molecular formula C₅H₈O and a molecular weight of approximately 84.12 g/mol. Its chemical structure and identifiers make it readily distinguishable for laboratory research, chemical sourcing, and synthesis planning.

Why Is 4-Pentyn-1-ol Useful in Organic Synthesis?

The value of 4-Pentyn-1-ol comes largely from its combination of an alcohol and terminal alkyne. Each functional group offers a different reaction pathway, allowing chemists to introduce additional functionality or connect the molecule with other building blocks.

The hydroxyl group can be modified through common alcohol transformations, including ether formation and esterification. Meanwhile, the terminal alkyne provides a reactive carbon-carbon triple bond that can be incorporated into more complex molecular structures.

This combination makes CAS NO: 5390-04-5 relevant to synthetic research where controlled functionalization and molecular construction are required. The compound has been documented as a useful synthetic intermediate, demonstrating its versatility in organic chemistry.

Key Chemical Features

Several characteristics make 4-Pentyn-1-ol attractive as a research building block:

• Terminal alkyne: The alkyne functionality provides a useful site for carbon-carbon bond-forming and other transformations.

• Primary alcohol: The hydroxyl group can undergo reactions typical of primary alcohols, enabling further functionalization.

• Small molecular size: With a molecular weight of approximately 84.12 g/mol, it can serve as a relatively compact fragment when constructing larger molecules.

• Bifunctional structure: Having two chemically useful functional groups in one molecule allows researchers to develop sequential or selective transformations.

These characteristics allow 4-Pentyn-1-ol to function as a flexible starting material in a variety of synthetic strategies.

Applications in Synthetic Chemistry

One of the most important roles of 4-Pentyn-1-ol is as an intermediate for synthesizing structurally more complex molecules. Researchers can modify either the alcohol or alkyne functionality depending on the desired synthetic route.

For example, the alcohol group can be converted into derivatives such as esters and ethers. The terminal alkyne can also participate in coupling chemistry and other transformations that introduce new carbon-carbon or carbon-heteroatom bonds. Such reactions can help researchers develop functionalized alkynes and more elaborate molecular frameworks.

Its bifunctional nature is particularly valuable when a synthetic sequence requires more than one point of molecular modification. Instead of introducing separate functional groups through multiple starting materials, researchers can use a molecule that already contains both an alcohol and an alkyne.

Role in Research and Development

4-Pentyn-1-ol can be relevant to research areas that require the construction of customized organic molecules. Its chemistry can support investigations involving synthetic intermediates, medicinal chemistry, functional molecules, and other areas of organic research.

The compound also has a documented history in synthetic chemistry. Established laboratory procedures describe its preparation, illustrating its recognition as a useful compound for organic synthesis.

For researchers sourcing CAS NO: 5390-04-5, factors such as purity, analytical documentation, packaging, and supplier specifications should be considered alongside price. Commercial specifications can vary, so checking the applicable certificate of analysis and product documentation is important before using a material in a particular synthesis.

Handling and Selection Considerations

As with other laboratory chemicals, 4-Pentyn-1-ol should be handled according to the supplier's current safety documentation and the requirements of the laboratory. Researchers should consult the applicable SDS for information concerning hazards, protective equipment, storage, handling, and disposal.

When selecting a material for research or production, it is useful to verify the chemical identity, purity, packaging requirements, analytical data, and availability. These considerations become especially important when the compound is being used as an intermediate where impurities could affect subsequent reactions.

Conclusion

CAS NO: 5390-04-5 identifies 4-Pentyn-1-ol, a versatile bifunctional compound combining a primary alcohol with a terminal alkyne. This distinctive structure gives organic chemists multiple opportunities for functionalization and makes the compound useful as a building block for developing more complex molecules.

Its applications in synthetic chemistry demonstrate why selecting a well-characterized material is important for reproducible research. By understanding its molecular structure, functional groups, potential transformations, and sourcing considerations, researchers can better evaluate where 4-Pentyn-1-ol fits into their synthetic strategy.

Other Recommendations: 3-BUTYN-1-OL Manufacturers